PDB Information

PDB4QGI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 lw12.3 isolate
Primary Citation
Defective Hydrophobic Sliding Mechanism and Active Site Expansion in HIV-1 Protease Drug Resistant Variant Gly48Thr/Leu89Met: Mechanisms for the Loss of Saquinavir Binding Potency.
Goldfarb, N.E., Ohanessian, M., Biswas, S., McGee, T.D., Mahon, B.P., Ostrov, D.A., Garcia, J., Tang, Y., McKenna, R., Roitberg, A., Dunn, B.M.
Biochemistry
HeaderHydrolase/Hydrolase Inhibitor
Released2014-05-22
Resolution1.900
CATH Insert Date27 Jul, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Jul, 2014 Chopped
B 28 Jul, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4qgiA00 03 Aug, 2014 2.40.70.10 Assigned
4qgiB00 03 Aug, 2014 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein