PDB Information

PDB4QCI
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta.
Kuai, J., Mosyak, L., Brooks, J., Cain, M., Carven, G.J., Ogawa, S., Ishino, T., Tam, M., Lavallie, E.R., Yang, Z., Ponsel, D., Rauchenberger, R., Arch, R., Pullen, N.
Biochemistry
HeaderCytokine/Cytokine Receptor
Released2014-05-12
Resolution2.300
CATH Insert Date28 Jun, 2015

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
H 29 Jun, 2015 Chopped
L 29 Jun, 2015 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4qciA01 04 Jul, 2016 2.60.40.10 Assigned
4qciA02 04 Jul, 2016 2.60.40.10 Assigned
4qciB01 10 Jul, 2015 2.60.40.10 Assigned
4qciB02 10 Jul, 2015 2.60.40.10 Assigned
4qciC00 09 Jul, 2015 2.10.90.10 Assigned
4qciD00 10 Jul, 2015 2.10.90.10 Assigned
4qciH01 10 Jul, 2015 2.60.40.10 Assigned
4qciH02 10 Jul, 2015 2.60.40.10 Assigned
4qciL01 04 Jul, 2016 2.60.40.10 Assigned
4qciL02 04 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P01127 PDGFB_HUMAN Homo sapiens Platelet-derived growth factor subunit B
P01127 PDGFB_HUMAN Homo sapiens Platelet-derived growth factor subunit B
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