PDB Information

PDB4PTE
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core.
Sivaprakasam, P., Han, X., Civiello, R.L., Jacutin-Porte, S., Kish, K., Pokross, M., Lewis, H.A., Ahmed, N., Szapiel, N., Newitt, J.A., Baldwin, E.T., Xiao, H., Krause, C.M., Park, H., Nophsker, M., Lippy, J.S., Burton, C.R., Langley, D.R., Macor, J.E., Dubowchik, G.M.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-03-10
Resolution2.030
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4pteA01 10 Jul, 2015 3.30.200.20 Assigned
4pteA02 10 Jul, 2015 1.10.510.10 Assigned
4pteB01 10 Jul, 2015 3.30.200.20 Assigned
4pteB02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta