PDB 4ppc

PDB Information

PDB4PPC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and optimization of indazoles as potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitors.
Pastor, R.M., Burch, J.D., Magnuson, S., Ortwine, D.F., Chen, Y., De La Torre, K., Ding, X., Eigenbrot, C., Johnson, A., Liimatta, M., Liu, Y., Shia, S., Wang, X., Wu, L.C., Pei, Z.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-02-26
Resolution2.950
CATH Insert Date15 Jun, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Jun, 2014 Chopped
B 16 Jun, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ppcA00 19 Jun, 2014 1.10.510.10 Assigned
4ppcB00 19 Jun, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK