PDB 4pl5

PDB Information

PDB4PL5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Sanches, M., Duffy, N.M., Talukdar, M., Thevakumaran, N., Chiovitti, D., Canny, M.D., Lee, K., Kurinov, I., Uehling, D., Al-Awar, R., Poda, G., Prakesch, M., Wilson, B., Tam, V., Schweitzer, C., Toro, A., Lucas, J.L., Vuga, D., Lehmann, L., Durocher, D., Zeng, Q., Patterson, J.B., Sicheri, F.
Nat Commun
HeaderTransferase,Hydrolase/Inhibitor
Released2014-05-16
Resolution3.400
CATH Insert Date14 Sep, 2014

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4pl5A01 16 Sep, 2014 3.30.200.20 Assigned
4pl5A02 16 Sep, 2014 1.10.510.10 Assigned
4pl5A03 16 Sep, 2014 1.20.1440.180 Assigned
4pl5B01 16 Sep, 2014 3.30.200.20 Assigned
4pl5B02 16 Sep, 2014 1.10.510.10 Assigned
4pl5B03 16 Sep, 2014 1.20.1440.180 Assigned
4pl5C01 16 Sep, 2014 3.30.200.20 Assigned
4pl5C02 16 Sep, 2014 1.10.510.10 Assigned
4pl5C03 16 Sep, 2014 1.20.1440.180 Assigned
4pl5D01 16 Sep, 2014 3.30.200.20 Assigned
4pl5D02 16 Sep, 2014 1.10.510.10 Assigned
4pl5D03 16 Sep, 2014 1.20.1440.180 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1