PDB 4pjt
PDB Information
| PDB | 4PJT |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone.
Acta Crystallogr.,Sect.F
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2014-05-12 |
| Resolution | 2.350 |
| CATH Insert Date | 05 Oct, 2014 |
PDB Images (13)
4pjt
PDB 4pjt
4pjtA
PDB Chain 4pjtA
4pjtB
PDB Chain 4pjtB
4pjtC
PDB Chain 4pjtC
4pjtD
PDB Chain 4pjtD
4pjtA01
CATH Domain 4pjtA01
4pjtA02
CATH Domain 4pjtA02
4pjtB01
CATH Domain 4pjtB01
4pjtB02
CATH Domain 4pjtB02
4pjtC01
CATH Domain 4pjtC01
4pjtC02
CATH Domain 4pjtC02
4pjtD01
CATH Domain 4pjtD01
4pjtD02
CATH Domain 4pjtD02
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 06 Oct, 2014 | Chopped |
| B | 06 Oct, 2014 | Chopped |
| C | 06 Oct, 2014 | Chopped |
| D | 06 Oct, 2014 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4pjtA01 | 08 Oct, 2014 | 1.20.142.10 | Assigned |
| 4pjtA02 | 08 Oct, 2014 | 3.90.228.10 | Assigned |
| 4pjtB01 | 08 Oct, 2014 | 1.20.142.10 | Assigned |
| 4pjtB02 | 08 Oct, 2014 | 3.90.228.10 | Assigned |
| 4pjtC01 | 08 Oct, 2014 | 1.20.142.10 | Assigned |
| 4pjtC02 | 08 Oct, 2014 | 3.90.228.10 | Assigned |
| 4pjtD01 | 08 Oct, 2014 | 1.20.142.10 | Assigned |
| 4pjtD02 | 08 Oct, 2014 | 3.90.228.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P09874 | PARP1_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase 1 |
| P09874 | PARP1_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase 1 |
| P09874 | PARP1_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase 1 |
| P09874 | PARP1_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase 1 |
