PDB Information

PDB4PIV
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A human fatty acid synthase inhibitor binds beta-ketoacyl reductase in the keto-substrate site.
Hardwicke, M.A., Rendina, A.R., Williams, S.P., Moore, M.L., Wang, L., Krueger, J.A., Plant, R.N., Totoritis, R.D., Zhang, G., Briand, J., Burkhart, W.A., Brown, K.K., Parrish, C.A.
Nat.Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2014-05-09
Resolution2.300
CATH Insert Date10 Aug, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Aug, 2014 Chopped
B 11 Aug, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4pivA01 27 Oct, 2014 Holding pen
4pivA02 27 Oct, 2014 3.40.50.720 Assigned
4pivB01 27 Oct, 2014 Holding pen
4pivB02 27 Oct, 2014 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase