PDB 4p90

PDB Links
Overview

PDB Information

PDB	4P90
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity. McCoull, W., Hennessy, E.J., Blades, K., Box, M.R., Chuaqui, C., Dowling, J.E., Davies, C.D., Ferguson, A.D., Goldberg, F.W., Howe, N.J., Kemmitt, P.D., Lamont, G.M., Madden, K., McWhirter, C., Varnes, J.G., Ward, R.A., Williams, J.D., Yang, B. MEDCHEMCOMM
Header	Transferase/Transferase Inhibitor
Released	2014-04-01
Resolution	2.490
CATH Insert Date	14 Sep, 2014

PDB Images (7)

Image of CATH 4p90

4p90

PDB 4p90

Image of CATH 4p90A

4p90A

PDB Chain 4p90A

Image of CATH 4p90B

4p90B

PDB Chain 4p90B

Image of CATH 4p90A01

4p90A01

CATH Domain 4p90A01

Image of CATH 4p90A02

4p90A02

CATH Domain 4p90A02

Image of CATH 4p90B01

4p90B01

CATH Domain 4p90B01

Image of CATH 4p90B02

4p90B02

CATH Domain 4p90B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 Sep, 2014	Chopped
B	15 Sep, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4p90A01	16 Sep, 2014	3.30.200.20	Assigned
4p90A02	16 Sep, 2014	1.10.510.10	Assigned
4p90B01	16 Sep, 2014	3.30.200.20	Assigned
4p90B02	16 Sep, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1