PDB 4p8l

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Overview

PDB Information

PDB	4P8L
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1. Neres, J., Hartkoorn, R.C., Chiarelli, L.R., Gadupudi, R., Pasca, M.R., Mori, G., Venturelli, A., Savina, S., Makarov, V., Kolly, G.S., Molteni, E., Binda, C., Dhar, N., Ferrari, S., Brodin, P., Delorme, V., Landry, V., de Jesus Lopes Ribeiro, A.L., Farina, D., Saxena, P., Pojer, F., Carta, A., Luciani, R., Porta, A., Zanoni, G., De Rossi, E., Costi, M.P., Riccardi, G., Cole, S.T. Acs Chem.Biol.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2014-03-31
Resolution	2.020
CATH Insert Date	21 Dec, 2014

PDB Images (5)

Image of CATH 4p8l

4p8l

PDB 4p8l

Image of CATH 4p8lA

4p8lA

PDB Chain 4p8lA

Image of CATH 4p8lB

4p8lB

PDB Chain 4p8lB

Image of CATH 4p8lA00

4p8lA00

CATH Domain 4p8lA00

Image of CATH 4p8lB00

4p8lB00

CATH Domain 4p8lB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	22 Dec, 2014	Chopped
B	22 Dec, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4p8lA00	28 Dec, 2014		Holding pen
4p8lB00	29 Dec, 2014		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P9WJF1	DPRE1_MYCTU	Mycobacterium tuberculosis H37Rv	Decaprenylphosphoryl-beta-D-ribose oxidase
P9WJF1	DPRE1_MYCTU	Mycobacterium tuberculosis H37Rv	Decaprenylphosphoryl-beta-D-ribose oxidase