PDB Information

PDB4P6G
MethodX-RAY DIFFRACTION
Host OrganismEnterobacteria phage L1
Gene SourceHomo sapiens
Primary Citation
Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm.
Jadhav, P.K., Schiffler, M.A., Gavardinas, K., Kim, E.J., Matthews, D.P., Staszak, M.A., Coffey, D.S., Shaw, B.W., Cassidy, K.C., Brier, R.A., Zhang, Y., Christie, R.M., Matter, W.F., Qing, K., Durbin, J.D., Wang, Y., Deng, G.G.
Acs Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-03-24
Resolution1.580
CATH Insert Date09 Nov, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped
B 10 Nov, 2014 Chopped
C 10 Nov, 2014 Chopped
D 10 Nov, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4p6gA00 13 Nov, 2014 3.90.70.10 Assigned
4p6gB00 12 Nov, 2014 3.90.70.10 Assigned
4p6gC00 13 Nov, 2014 3.90.70.10 Assigned
4p6gD00 13 Nov, 2014 3.90.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S