PDB Information

PDB4OBO
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization.
Crawford, T.D., Ndubaku, C.O., Chen, H., Boggs, J.W., Bravo, B.J., Delatorre, K., Giannetti, A.M., Gould, S.E., Harris, S.F., Magnuson, S.R., McNamara, E., Murray, L.J., Nonomiya, J., Sambrone, A., Schmidt, S., Smyczek, T., Stanley, M., Vitorino, P., Wang, L., West, K., Wu, P., Ye, W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-01-07
Resolution2.100
CATH Insert Date27 Apr, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Apr, 2014 Chopped
B 28 Apr, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4oboA01 03 May, 2014 3.30.200.20 Assigned
4oboA02 03 May, 2014 1.10.510.10 Assigned
4oboB01 03 May, 2014 3.30.200.20 Assigned
4oboB02 03 May, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O95819 M4K4_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4
O95819 M4K4_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase kinase 4
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