PDB 4o6e

PDB Information

PDB4O6E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2.
Blake, J.F., Gaudino, J.J., De Meese, J., Mohr, P., Chicarelli, M., Tian, H., Garrey, R., Thomas, A., Siedem, C.S., Welch, M.B., Kolakowski, G., Kaus, R., Burkard, M., Martinson, M., Chen, H., Dean, B., Dudley, D.A., Gould, S.E., Pacheco, P., Shahidi-Latham, S., Wang, W., West, K., Yin, J., Moffat, J., Schwarz, J.B.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-12-20
Resolution1.950
CATH Insert Date25 May, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4o6eA01 28 May, 2014 3.30.200.20 Assigned
4o6eA02 28 May, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1