PDB Information

PDB4O6A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Zhang, X., Wu, J., Du, F., Xu, H., Sun, L., Chen, Z., Brautigam, C.A., Zhang, X., Chen, Z.J.
Cell Rep
HeaderTransferase/Dna
Released2013-12-20
Resolution1.860
CATH Insert Date09 Feb, 2014

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 10 Feb, 2014 Chopped
B 10 Feb, 2014 Chopped
C 10 Feb, 2014 Rejected
D 10 Feb, 2014 Rejected
E 10 Feb, 2014 Rejected
F 10 Feb, 2014 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4o6aA01 07 Mar, 2014 1.10.1410.40 Assigned
4o6aA02 07 Mar, 2014 3.30.460.90 Assigned
4o6aB01 07 Mar, 2014 1.10.1410.40 Assigned
4o6aB02 07 Mar, 2014 3.30.460.90 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8C6L5 CGAS_MOUSE Mus musculus Cyclic GMP-AMP synthase
Q8C6L5 CGAS_MOUSE Mus musculus Cyclic GMP-AMP synthase