PDB Information

PDB4O2P
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceGallus gallus
Primary Citation
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against Neuroblastoma.
Tintori, C., Fallacara, A.L., Radi, M., Zamperini, C., Dreassi, E., Crespan, E., Maga, G., Schenone, S., Musumeci, F., Brullo, C., Richters, A., Gasparrini, F., Angelucci, A., Festuccia, C., Delle Monache, S., Rauh, D., Botta, M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-12-17
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4o2pA01 09 Jul, 2015 3.30.200.20 Assigned
4o2pA02 09 Jul, 2015 1.10.510.10 Assigned
4o2pB01 09 Jul, 2015 3.30.200.20 Assigned
4o2pB02 09 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00523 SRC_CHICK Gallus gallus Proto-oncogene tyrosine-protein kinase Src
P00523 SRC_CHICK Gallus gallus Proto-oncogene tyrosine-protein kinase Src