PDB 4o1m

PDB Information

PDB4O1M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceToxoplasma gondii
Primary Citation
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target
Wilkinson, C., Mcphillie, M.J., Zhou, Y., Woods, S., Afanador, G.A., Rawson, S., Khaliq, F., Prigge, S.T., Roberts, C.W., Rice, D.W., Mcleod, R., Fishwick, C.W., Muench, S.P.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2013-12-16
Resolution2.000
CATH Insert Date09 Feb, 2014

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 10 Feb, 2014 Chopped
B 10 Feb, 2014 Chopped
C 10 Feb, 2014 Chopped
D 10 Feb, 2014 Chopped
E 10 Feb, 2014 Chopped
F 10 Feb, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4o1mA00 07 Mar, 2014 3.40.50.720 Assigned
4o1mB00 07 Mar, 2014 3.40.50.720 Assigned
4o1mC00 07 Mar, 2014 3.40.50.720 Assigned
4o1mD00 07 Mar, 2014 3.40.50.720 Assigned
4o1mE00 07 Mar, 2014 3.40.50.720 Assigned
4o1mF00 07 Mar, 2014 3.40.50.720 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase
Q6UCJ9 Q6UCJ9_TOXGO Toxoplasma gondii Enoyl-acyl carrier reductase