PDB 4nwm

PDB Information

PDB4NWM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Purine derivatives as potent Bruton's tyrosine kinase (BTK) inhibitors for autoimmune diseases.
Shi, Q., Tebben, A., Dyckman, A.J., Li, H., Liu, C., Lin, J., Spergel, S., Burke, J.R., McIntyre, K.W., Olini, G.C., Strnad, J., Surti, N., Muckelbauer, J.K., Chang, C., An, Y., Cheng, L., Ruan, Q., Leftheris, K., Carter, P.H., Tino, J., De Lucca, G.V.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-12-06
Resolution2.030
CATH Insert Date06 Apr, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped
B 07 Apr, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4nwmA01 25 Apr, 2014 3.30.200.20 Assigned
4nwmA02 25 Apr, 2014 1.10.510.10 Assigned
4nwmB01 25 Apr, 2014 3.30.200.20 Assigned
4nwmB02 25 Apr, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK