PDB 4no8

PDB Links
Overview

PDB Information

PDB	4NO8
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Stein, M.L., Cui, H., Beck, P., Dubiella, C., Voss, C., Kruger, A., Schmidt, B., Groll, M. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-11-19
Resolution	2.700
CATH Insert Date	16 Feb, 2014

PDB Images (57)

4no8

PDB 4no8

4no8a

PDB Chain 4no8a

4no8A

PDB Chain 4no8A

4no8b

PDB Chain 4no8b

4no8B

PDB Chain 4no8B

4no8C

PDB Chain 4no8C

4no8D

PDB Chain 4no8D

4no8E

PDB Chain 4no8E

4no8F

PDB Chain 4no8F

4no8G

PDB Chain 4no8G

4no8H

PDB Chain 4no8H

4no8I

PDB Chain 4no8I

4no8J

PDB Chain 4no8J

4no8K

PDB Chain 4no8K

4no8L

PDB Chain 4no8L

4no8M

PDB Chain 4no8M

4no8N

PDB Chain 4no8N

4no8O

PDB Chain 4no8O

4no8P

PDB Chain 4no8P

4no8Q

PDB Chain 4no8Q

4no8R

PDB Chain 4no8R

4no8S

PDB Chain 4no8S

4no8T

PDB Chain 4no8T

4no8U

PDB Chain 4no8U

4no8V

PDB Chain 4no8V

4no8W

PDB Chain 4no8W

4no8X

PDB Chain 4no8X

4no8Y

PDB Chain 4no8Y

4no8Z

PDB Chain 4no8Z

4no8a00

CATH Domain 4no8a00

4no8A00

CATH Domain 4no8A00

4no8b00

CATH Domain 4no8b00

4no8B00

CATH Domain 4no8B00

4no8C00

CATH Domain 4no8C00

4no8D00

CATH Domain 4no8D00

4no8E00

CATH Domain 4no8E00

4no8F00

CATH Domain 4no8F00

4no8G00

CATH Domain 4no8G00

4no8H00

CATH Domain 4no8H00

4no8I00

CATH Domain 4no8I00

4no8J00

CATH Domain 4no8J00

4no8K00

CATH Domain 4no8K00

4no8L00

CATH Domain 4no8L00

4no8M00

CATH Domain 4no8M00

4no8N00

CATH Domain 4no8N00

4no8O00

CATH Domain 4no8O00

4no8P00

CATH Domain 4no8P00

4no8Q00

CATH Domain 4no8Q00

4no8R00

CATH Domain 4no8R00

4no8S00

CATH Domain 4no8S00

4no8T00

CATH Domain 4no8T00

4no8U00

CATH Domain 4no8U00

4no8V00

CATH Domain 4no8V00

4no8W00

CATH Domain 4no8W00

4no8X00

CATH Domain 4no8X00

4no8Y00

CATH Domain 4no8Y00

4no8Z00

CATH Domain 4no8Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	17 Feb, 2014	Chopped
A	17 Feb, 2014	Chopped
b	17 Feb, 2014	Chopped
B	17 Feb, 2014	Chopped
C	17 Feb, 2014	Chopped
D	17 Feb, 2014	Chopped
E	17 Feb, 2014	Chopped
F	17 Feb, 2014	Chopped
G	17 Feb, 2014	Chopped
H	17 Feb, 2014	Chopped
I	17 Feb, 2014	Chopped
J	17 Feb, 2014	Chopped
K	17 Feb, 2014	Chopped
L	17 Feb, 2014	Chopped
M	17 Feb, 2014	Chopped
N	17 Feb, 2014	Chopped
O	17 Feb, 2014	Chopped
P	17 Feb, 2014	Chopped
Q	17 Feb, 2014	Chopped
R	17 Feb, 2014	Chopped
S	17 Feb, 2014	Chopped
T	17 Feb, 2014	Chopped
U	17 Feb, 2014	Chopped
V	17 Feb, 2014	Chopped
W	17 Feb, 2014	Chopped
X	17 Feb, 2014	Chopped
Y	17 Feb, 2014	Chopped
Z	17 Feb, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4no8a00	07 Mar, 2014	3.60.20.10	Assigned
4no8A00	07 Mar, 2014	3.60.20.10	Assigned
4no8b00	07 Mar, 2014	3.60.20.10	Assigned
4no8B00	07 Mar, 2014	3.60.20.10	Assigned
4no8C00	07 Mar, 2014	3.60.20.10	Assigned
4no8D00	07 Mar, 2014	3.60.20.10	Assigned
4no8E00	07 Mar, 2014	3.60.20.10	Assigned
4no8F00	07 Mar, 2014	3.60.20.10	Assigned
4no8G00	07 Mar, 2014	3.60.20.10	Assigned
4no8H00	07 Mar, 2014	3.60.20.10	Assigned
4no8I00	07 Mar, 2014	3.60.20.10	Assigned
4no8J00	07 Mar, 2014	3.60.20.10	Assigned
4no8K00	07 Mar, 2014	3.60.20.10	Assigned
4no8L00	07 Mar, 2014	3.60.20.10	Assigned
4no8M00	07 Mar, 2014	3.60.20.10	Assigned
4no8N00	07 Mar, 2014	3.60.20.10	Assigned
4no8O00	07 Mar, 2014	3.60.20.10	Assigned
4no8P00	07 Mar, 2014	3.60.20.10	Assigned
4no8Q00	07 Mar, 2014	3.60.20.10	Assigned
4no8R00	07 Mar, 2014	3.60.20.10	Assigned
4no8S00	07 Mar, 2014	3.60.20.10	Assigned
4no8T00	07 Mar, 2014	3.60.20.10	Assigned
4no8U00	07 Mar, 2014	3.60.20.10	Assigned
4no8V00	07 Mar, 2014	3.60.20.10	Assigned
4no8W00	07 Mar, 2014	3.60.20.10	Assigned
4no8X00	07 Mar, 2014	3.60.20.10	Assigned
4no8Y00	07 Mar, 2014	3.60.20.10	Assigned
4no8Z00	07 Mar, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5