PDB 4no6

PDB Links
Overview

PDB Information

PDB	4NO6
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Stein, M.L., Cui, H., Beck, P., Dubiella, C., Voss, C., Kruger, A., Schmidt, B., Groll, M. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-11-19
Resolution	3.000
CATH Insert Date	16 Feb, 2014

PDB Images (57)

4no6

PDB 4no6

4no6a

PDB Chain 4no6a

4no6A

PDB Chain 4no6A

4no6b

PDB Chain 4no6b

4no6B

PDB Chain 4no6B

4no6C

PDB Chain 4no6C

4no6D

PDB Chain 4no6D

4no6E

PDB Chain 4no6E

4no6F

PDB Chain 4no6F

4no6G

PDB Chain 4no6G

4no6H

PDB Chain 4no6H

4no6I

PDB Chain 4no6I

4no6J

PDB Chain 4no6J

4no6K

PDB Chain 4no6K

4no6L

PDB Chain 4no6L

4no6M

PDB Chain 4no6M

4no6N

PDB Chain 4no6N

4no6O

PDB Chain 4no6O

4no6P

PDB Chain 4no6P

4no6Q

PDB Chain 4no6Q

4no6R

PDB Chain 4no6R

4no6S

PDB Chain 4no6S

4no6T

PDB Chain 4no6T

4no6U

PDB Chain 4no6U

4no6V

PDB Chain 4no6V

4no6W

PDB Chain 4no6W

4no6X

PDB Chain 4no6X

4no6Y

PDB Chain 4no6Y

4no6Z

PDB Chain 4no6Z

4no6a00

CATH Domain 4no6a00

4no6A00

CATH Domain 4no6A00

4no6b00

CATH Domain 4no6b00

4no6B00

CATH Domain 4no6B00

4no6C00

CATH Domain 4no6C00

4no6D00

CATH Domain 4no6D00

4no6E00

CATH Domain 4no6E00

4no6F00

CATH Domain 4no6F00

4no6G00

CATH Domain 4no6G00

4no6H00

CATH Domain 4no6H00

4no6I00

CATH Domain 4no6I00

4no6J00

CATH Domain 4no6J00

4no6K00

CATH Domain 4no6K00

4no6L00

CATH Domain 4no6L00

4no6M00

CATH Domain 4no6M00

4no6N00

CATH Domain 4no6N00

4no6O00

CATH Domain 4no6O00

4no6P00

CATH Domain 4no6P00

4no6Q00

CATH Domain 4no6Q00

4no6R00

CATH Domain 4no6R00

4no6S00

CATH Domain 4no6S00

4no6T00

CATH Domain 4no6T00

4no6U00

CATH Domain 4no6U00

4no6V00

CATH Domain 4no6V00

4no6W00

CATH Domain 4no6W00

4no6X00

CATH Domain 4no6X00

4no6Y00

CATH Domain 4no6Y00

4no6Z00

CATH Domain 4no6Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	17 Feb, 2014	Chopped
A	17 Feb, 2014	Chopped
b	17 Feb, 2014	Chopped
B	17 Feb, 2014	Chopped
C	17 Feb, 2014	Chopped
D	17 Feb, 2014	Chopped
E	17 Feb, 2014	Chopped
F	17 Feb, 2014	Chopped
G	17 Feb, 2014	Chopped
H	17 Feb, 2014	Chopped
I	17 Feb, 2014	Chopped
J	17 Feb, 2014	Chopped
K	17 Feb, 2014	Chopped
L	17 Feb, 2014	Chopped
M	17 Feb, 2014	Chopped
N	17 Feb, 2014	Chopped
O	17 Feb, 2014	Chopped
P	17 Feb, 2014	Chopped
Q	17 Feb, 2014	Chopped
R	17 Feb, 2014	Chopped
S	17 Feb, 2014	Chopped
T	17 Feb, 2014	Chopped
U	17 Feb, 2014	Chopped
V	17 Feb, 2014	Chopped
W	17 Feb, 2014	Chopped
X	17 Feb, 2014	Chopped
Y	17 Feb, 2014	Chopped
Z	17 Feb, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4no6a00	07 Mar, 2014	3.60.20.10	Assigned
4no6A00	07 Mar, 2014	3.60.20.10	Assigned
4no6b00	07 Mar, 2014	3.60.20.10	Assigned
4no6B00	07 Mar, 2014	3.60.20.10	Assigned
4no6C00	07 Mar, 2014	3.60.20.10	Assigned
4no6D00	07 Mar, 2014	3.60.20.10	Assigned
4no6E00	07 Mar, 2014	3.60.20.10	Assigned
4no6F00	07 Mar, 2014	3.60.20.10	Assigned
4no6G00	07 Mar, 2014	3.60.20.10	Assigned
4no6H00	07 Mar, 2014	3.60.20.10	Assigned
4no6I00	07 Mar, 2014	3.60.20.10	Assigned
4no6J00	07 Mar, 2014	3.60.20.10	Assigned
4no6K00	07 Mar, 2014	3.60.20.10	Assigned
4no6L00	07 Mar, 2014	3.60.20.10	Assigned
4no6M00	07 Mar, 2014	3.60.20.10	Assigned
4no6N00	07 Mar, 2014	3.60.20.10	Assigned
4no6O00	07 Mar, 2014	3.60.20.10	Assigned
4no6P00	07 Mar, 2014	3.60.20.10	Assigned
4no6Q00	07 Mar, 2014	3.60.20.10	Assigned
4no6R00	07 Mar, 2014	3.60.20.10	Assigned
4no6S00	07 Mar, 2014	3.60.20.10	Assigned
4no6T00	07 Mar, 2014	3.60.20.10	Assigned
4no6U00	07 Mar, 2014	3.60.20.10	Assigned
4no6V00	07 Mar, 2014	3.60.20.10	Assigned
4no6W00	07 Mar, 2014	3.60.20.10	Assigned
4no6X00	07 Mar, 2014	3.60.20.10	Assigned
4no6Y00	07 Mar, 2014	3.60.20.10	Assigned
4no6Z00	07 Mar, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5