PDB 4nnw

PDB Links
Overview

PDB Information

PDB	4NNW
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Stein, M.L., Cui, H., Beck, P., Dubiella, C., Voss, C., Kruger, A., Schmidt, B., Groll, M. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-11-19
Resolution	2.600
CATH Insert Date	16 Feb, 2014

PDB Images (57)

4nnw

PDB 4nnw

4nnwa

PDB Chain 4nnwa

4nnwA

PDB Chain 4nnwA

4nnwb

PDB Chain 4nnwb

4nnwB

PDB Chain 4nnwB

4nnwC

PDB Chain 4nnwC

4nnwD

PDB Chain 4nnwD

4nnwE

PDB Chain 4nnwE

4nnwF

PDB Chain 4nnwF

4nnwG

PDB Chain 4nnwG

4nnwH

PDB Chain 4nnwH

4nnwI

PDB Chain 4nnwI

4nnwJ

PDB Chain 4nnwJ

4nnwK

PDB Chain 4nnwK

4nnwL

PDB Chain 4nnwL

4nnwM

PDB Chain 4nnwM

4nnwN

PDB Chain 4nnwN

4nnwO

PDB Chain 4nnwO

4nnwP

PDB Chain 4nnwP

4nnwQ

PDB Chain 4nnwQ

4nnwR

PDB Chain 4nnwR

4nnwS

PDB Chain 4nnwS

4nnwT

PDB Chain 4nnwT

4nnwU

PDB Chain 4nnwU

4nnwV

PDB Chain 4nnwV

4nnwW

PDB Chain 4nnwW

4nnwX

PDB Chain 4nnwX

4nnwY

PDB Chain 4nnwY

4nnwZ

PDB Chain 4nnwZ

4nnwa00

CATH Domain 4nnwa00

4nnwA00

CATH Domain 4nnwA00

4nnwb00

CATH Domain 4nnwb00

4nnwB00

CATH Domain 4nnwB00

4nnwC00

CATH Domain 4nnwC00

4nnwD00

CATH Domain 4nnwD00

4nnwE00

CATH Domain 4nnwE00

4nnwF00

CATH Domain 4nnwF00

4nnwG00

CATH Domain 4nnwG00

4nnwH00

CATH Domain 4nnwH00

4nnwI00

CATH Domain 4nnwI00

4nnwJ00

CATH Domain 4nnwJ00

4nnwK00

CATH Domain 4nnwK00

4nnwL00

CATH Domain 4nnwL00

4nnwM00

CATH Domain 4nnwM00

4nnwN00

CATH Domain 4nnwN00

4nnwO00

CATH Domain 4nnwO00

4nnwP00

CATH Domain 4nnwP00

4nnwQ00

CATH Domain 4nnwQ00

4nnwR00

CATH Domain 4nnwR00

4nnwS00

CATH Domain 4nnwS00

4nnwT00

CATH Domain 4nnwT00

4nnwU00

CATH Domain 4nnwU00

4nnwV00

CATH Domain 4nnwV00

4nnwW00

CATH Domain 4nnwW00

4nnwX00

CATH Domain 4nnwX00

4nnwY00

CATH Domain 4nnwY00

4nnwZ00

CATH Domain 4nnwZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	17 Feb, 2014	Chopped
A	17 Feb, 2014	Chopped
b	17 Feb, 2014	Chopped
B	17 Feb, 2014	Chopped
C	17 Feb, 2014	Chopped
D	17 Feb, 2014	Chopped
E	17 Feb, 2014	Chopped
F	17 Feb, 2014	Chopped
G	17 Feb, 2014	Chopped
H	17 Feb, 2014	Chopped
I	17 Feb, 2014	Chopped
J	17 Feb, 2014	Chopped
K	17 Feb, 2014	Chopped
L	17 Feb, 2014	Chopped
M	17 Feb, 2014	Chopped
N	17 Feb, 2014	Chopped
O	17 Feb, 2014	Chopped
P	17 Feb, 2014	Chopped
Q	17 Feb, 2014	Chopped
R	17 Feb, 2014	Chopped
S	17 Feb, 2014	Chopped
T	17 Feb, 2014	Chopped
U	17 Feb, 2014	Chopped
V	17 Feb, 2014	Chopped
W	17 Feb, 2014	Chopped
X	17 Feb, 2014	Chopped
Y	17 Feb, 2014	Chopped
Z	17 Feb, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4nnwa00	07 Mar, 2014	3.60.20.10	Assigned
4nnwA00	07 Mar, 2014	3.60.20.10	Assigned
4nnwb00	07 Mar, 2014	3.60.20.10	Assigned
4nnwB00	07 Mar, 2014	3.60.20.10	Assigned
4nnwC00	07 Mar, 2014	3.60.20.10	Assigned
4nnwD00	07 Mar, 2014	3.60.20.10	Assigned
4nnwE00	07 Mar, 2014	3.60.20.10	Assigned
4nnwF00	07 Mar, 2014	3.60.20.10	Assigned
4nnwG00	07 Mar, 2014	3.60.20.10	Assigned
4nnwH00	07 Mar, 2014	3.60.20.10	Assigned
4nnwI00	07 Mar, 2014	3.60.20.10	Assigned
4nnwJ00	07 Mar, 2014	3.60.20.10	Assigned
4nnwK00	07 Mar, 2014	3.60.20.10	Assigned
4nnwL00	07 Mar, 2014	3.60.20.10	Assigned
4nnwM00	07 Mar, 2014	3.60.20.10	Assigned
4nnwN00	07 Mar, 2014	3.60.20.10	Assigned
4nnwO00	07 Mar, 2014	3.60.20.10	Assigned
4nnwP00	07 Mar, 2014	3.60.20.10	Assigned
4nnwQ00	07 Mar, 2014	3.60.20.10	Assigned
4nnwR00	07 Mar, 2014	3.60.20.10	Assigned
4nnwS00	07 Mar, 2014	3.60.20.10	Assigned
4nnwT00	07 Mar, 2014	3.60.20.10	Assigned
4nnwU00	07 Mar, 2014	3.60.20.10	Assigned
4nnwV00	07 Mar, 2014	3.60.20.10	Assigned
4nnwW00	07 Mar, 2014	3.60.20.10	Assigned
4nnwX00	07 Mar, 2014	3.60.20.10	Assigned
4nnwY00	07 Mar, 2014	3.60.20.10	Assigned
4nnwZ00	07 Mar, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5