PDB 4nnn

PDB Links
Overview

PDB Information

PDB	4NNN
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the alpha-Ketoamide Electrophile as an Auspicious Reversible Lead Motif. Stein, M.L., Cui, H., Beck, P., Dubiella, C., Voss, C., Kruger, A., Schmidt, B., Groll, M. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-11-18
Resolution	2.500
CATH Insert Date	16 Feb, 2014

PDB Images (57)

4nnn

PDB 4nnn

4nnna

PDB Chain 4nnna

4nnnA

PDB Chain 4nnnA

4nnnb

PDB Chain 4nnnb

4nnnB

PDB Chain 4nnnB

4nnnC

PDB Chain 4nnnC

4nnnD

PDB Chain 4nnnD

4nnnE

PDB Chain 4nnnE

4nnnF

PDB Chain 4nnnF

4nnnG

PDB Chain 4nnnG

4nnnH

PDB Chain 4nnnH

4nnnI

PDB Chain 4nnnI

4nnnJ

PDB Chain 4nnnJ

4nnnK

PDB Chain 4nnnK

4nnnL

PDB Chain 4nnnL

4nnnM

PDB Chain 4nnnM

4nnnN

PDB Chain 4nnnN

4nnnO

PDB Chain 4nnnO

4nnnP

PDB Chain 4nnnP

4nnnQ

PDB Chain 4nnnQ

4nnnR

PDB Chain 4nnnR

4nnnS

PDB Chain 4nnnS

4nnnT

PDB Chain 4nnnT

4nnnU

PDB Chain 4nnnU

4nnnV

PDB Chain 4nnnV

4nnnW

PDB Chain 4nnnW

4nnnX

PDB Chain 4nnnX

4nnnY

PDB Chain 4nnnY

4nnnZ

PDB Chain 4nnnZ

4nnna00

CATH Domain 4nnna00

4nnnA00

CATH Domain 4nnnA00

4nnnb00

CATH Domain 4nnnb00

4nnnB00

CATH Domain 4nnnB00

4nnnC00

CATH Domain 4nnnC00

4nnnD00

CATH Domain 4nnnD00

4nnnE00

CATH Domain 4nnnE00

4nnnF00

CATH Domain 4nnnF00

4nnnG00

CATH Domain 4nnnG00

4nnnH00

CATH Domain 4nnnH00

4nnnI00

CATH Domain 4nnnI00

4nnnJ00

CATH Domain 4nnnJ00

4nnnK00

CATH Domain 4nnnK00

4nnnL00

CATH Domain 4nnnL00

4nnnM00

CATH Domain 4nnnM00

4nnnN00

CATH Domain 4nnnN00

4nnnO00

CATH Domain 4nnnO00

4nnnP00

CATH Domain 4nnnP00

4nnnQ00

CATH Domain 4nnnQ00

4nnnR00

CATH Domain 4nnnR00

4nnnS00

CATH Domain 4nnnS00

4nnnT00

CATH Domain 4nnnT00

4nnnU00

CATH Domain 4nnnU00

4nnnV00

CATH Domain 4nnnV00

4nnnW00

CATH Domain 4nnnW00

4nnnX00

CATH Domain 4nnnX00

4nnnY00

CATH Domain 4nnnY00

4nnnZ00

CATH Domain 4nnnZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	17 Feb, 2014	Chopped
A	17 Feb, 2014	Chopped
b	17 Feb, 2014	Chopped
B	17 Feb, 2014	Chopped
C	17 Feb, 2014	Chopped
D	17 Feb, 2014	Chopped
E	17 Feb, 2014	Chopped
F	17 Feb, 2014	Chopped
G	17 Feb, 2014	Chopped
H	17 Feb, 2014	Chopped
I	17 Feb, 2014	Chopped
J	17 Feb, 2014	Chopped
K	17 Feb, 2014	Chopped
L	17 Feb, 2014	Chopped
M	17 Feb, 2014	Chopped
N	17 Feb, 2014	Chopped
O	17 Feb, 2014	Chopped
P	17 Feb, 2014	Chopped
Q	17 Feb, 2014	Chopped
R	17 Feb, 2014	Chopped
S	17 Feb, 2014	Chopped
T	17 Feb, 2014	Chopped
U	17 Feb, 2014	Chopped
V	17 Feb, 2014	Chopped
W	17 Feb, 2014	Chopped
X	17 Feb, 2014	Chopped
Y	17 Feb, 2014	Chopped
Z	17 Feb, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4nnna00	07 Mar, 2014	3.60.20.10	Assigned
4nnnA00	07 Mar, 2014	3.60.20.10	Assigned
4nnnb00	07 Mar, 2014	3.60.20.10	Assigned
4nnnB00	07 Mar, 2014	3.60.20.10	Assigned
4nnnC00	07 Mar, 2014	3.60.20.10	Assigned
4nnnD00	07 Mar, 2014	3.60.20.10	Assigned
4nnnE00	07 Mar, 2014	3.60.20.10	Assigned
4nnnF00	07 Mar, 2014	3.60.20.10	Assigned
4nnnG00	07 Mar, 2014	3.60.20.10	Assigned
4nnnH00	07 Mar, 2014	3.60.20.10	Assigned
4nnnI00	07 Mar, 2014	3.60.20.10	Assigned
4nnnJ00	07 Mar, 2014	3.60.20.10	Assigned
4nnnK00	07 Mar, 2014	3.60.20.10	Assigned
4nnnL00	07 Mar, 2014	3.60.20.10	Assigned
4nnnM00	07 Mar, 2014	3.60.20.10	Assigned
4nnnN00	07 Mar, 2014	3.60.20.10	Assigned
4nnnO00	07 Mar, 2014	3.60.20.10	Assigned
4nnnP00	07 Mar, 2014	3.60.20.10	Assigned
4nnnQ00	07 Mar, 2014	3.60.20.10	Assigned
4nnnR00	07 Mar, 2014	3.60.20.10	Assigned
4nnnS00	07 Mar, 2014	3.60.20.10	Assigned
4nnnT00	07 Mar, 2014	3.60.20.10	Assigned
4nnnU00	07 Mar, 2014	3.60.20.10	Assigned
4nnnV00	07 Mar, 2014	3.60.20.10	Assigned
4nnnW00	07 Mar, 2014	3.60.20.10	Assigned
4nnnX00	07 Mar, 2014	3.60.20.10	Assigned
4nnnY00	07 Mar, 2014	3.60.20.10	Assigned
4nnnZ00	07 Mar, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5