PDB Information

PDB4NMH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Identification and optimisation of 3,3-dimethyl-azetidin-2-ones as potent and selective inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1)
McCoull, W., Augustin, M., Blake, C., Ertan, A., Kilgour, E.K., Krapp, S., Moore, J.E., Newcombe, N.J., Packer, M.J., Rees, A., Revill, J., Scott, J.S., Selmi, N., Gerhardt, S., Ogg, D.J., Steinbacher, S., Whittamore, P.R.O.
TO BE PUBLISHED
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-11-15
Resolution2.900
CATH Insert Date30 Mar, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 31 Mar, 2014 Chopped
B 31 Mar, 2014 Chopped
C 31 Mar, 2014 Chopped
D 31 Mar, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4nmhA00 25 Apr, 2014 3.40.50.720 Assigned
4nmhB00 25 Apr, 2014 3.40.50.720 Assigned
4nmhC00 25 Apr, 2014 3.40.50.720 Assigned
4nmhD00 25 Apr, 2014 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1