PDB Information

PDB4NKS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
FGFR1 Kinase Inhibitors: Close Regioisomers Adopt Divergent Binding Modes and Display Distinct Biophysical Signatures.
Klein, T., Tucker, J., Holdgate, G.A., Norman, R.A., Breeze, A.L.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-11-13
Resolution2.500
CATH Insert Date22 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4nksA01 26 Dec, 2013 3.30.200.20 Assigned
4nksA02 26 Dec, 2013 1.10.510.10 Assigned
4nksB01 26 Dec, 2013 3.30.200.20 Assigned
4nksB02 26 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1