PDB Information

PDB4NJS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Yedidi, R.S., Garimella, H., Aoki, M., Aoki-Ogata, H., Desai, D.V., Chang, S.B., Davis, D.A., Fyvie, W.S., Kaufman, J.D., Smith, D.W., Das, D., Wingfield, P.T., Maeda, K., Ghosh, A.K., Mitsuya, H.
Antimicrob.Agents Chemother.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-11-11
Resolution1.800
CATH Insert Date06 Apr, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped
B 07 Apr, 2014 Chopped
C 07 Apr, 2014 Chopped
D 07 Apr, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4njsA00 25 Apr, 2014 2.40.70.10 Assigned
4njsB00 25 Apr, 2014 2.40.70.10 Assigned
4njsC00 25 Apr, 2014 2.40.70.10 Assigned
4njsD00 25 Apr, 2014 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease