PDB Information

PDB4NCX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum 3D7
Primary Citation
Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase.
Nakazawa Hewitt, S., Dranow, D.M., Horst, B.G., Abendroth, J.A., Forte, B., Hallyburton, I., Jansen, C., Baragana, B., Choi, R., Rivas, K.L., Hulverson, M.A., Dumais, M., Edwards, T.E., Lorimer, D.D., Fairlamb, A.H., Gray, D.W., Read, K.D., Lehane, A.M., Kirk, K., Myler, P.J., Wernimont, A., Walpole, C.S., Stacy, R., Barrett, L.K., Gilbert, I.H., Van Voorhis, W.C.
ACS Infect Dis
HeaderLigase
Released2013-10-25
Resolution1.850
CATH Insert Date09 Nov, 2014

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped
B 10 Nov, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ncxA01 22 Dec, 2016 3.30.930.10 Assigned
4ncxA02 22 Dec, 2016 3.40.50.800 Assigned
4ncxA03 22 Dec, 2016 3.30.110.30 Assigned
4ncxB01 20 Apr, 2015 3.30.930.10 Assigned
4ncxB02 20 Apr, 2015 3.40.50.800 Assigned
4ncxB03 20 Apr, 2015 3.30.110.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8I5R7 SYP_PLAF7 Plasmodium falciparum 3D7 Proline--tRNA ligase
Q8I5R7 SYP_PLAF7 Plasmodium falciparum 3D7 Proline--tRNA ligase