PDB Information

PDB4NAU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Discovery of Inhibitors of 4'-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy.
de Jonge, B.L., Walkup, G.K., Lahiri, S.D., Huynh, H., Neckermann, G., Utley, L., Nash, T.J., Brock, J., San Martin, M., Kutschke, A., Johnstone, M., Laganas, V., Hajec, L., Gu, R.F., Ni, H., Chen, B., Hutchings, K., Holt, E., McKinney, D., Gao, N., Livchak, S., Thresher, J.
Antimicrob.Agents Chemother.
HeaderTransferase/Transferase Inhibitor
Released2013-10-22
Resolution2.330
CATH Insert Date16 Mar, 2014

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2014 Chopped
B 17 Mar, 2014 Chopped
C 17 Mar, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4nauA00 25 Apr, 2014 3.40.50.620 Assigned
4nauB00 25 Apr, 2014 3.40.50.620 Assigned
4nauC00 25 Apr, 2014 3.40.50.620 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase