PDB 4nah

PDB Information

PDB4NAH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Discovery of inhibitors of 4'-phosphopantetheine adenylyltransferase (PPAT) to validate PPAT as a target for antibacterial therapy.
de Jonge, B.L., Walkup, G.K., Lahiri, S.D., Huynh, H., Neckermann, G., Utley, L., Nash, T.J., Brock, J., San Martin, M., Kutschke, A., Johnstone, M., Laganas, V., Hajec, L., Gu, R.F., Ni, H., Chen, B., Hutchings, K., Holt, E., McKinney, D., Gao, N., Livchak, S., Thresher, J.
Antimicrob.Agents Chemother.
HeaderTransferase/Transferase Inhibitor
Released2013-10-22
Resolution2.380
CATH Insert Date16 Mar, 2014

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2014 Chopped
B 17 Mar, 2014 Chopped
C 17 Mar, 2014 Chopped
D 17 Mar, 2014 Chopped
E 17 Mar, 2014 Chopped
F 17 Mar, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4nahA00 25 Apr, 2014 3.40.50.620 Assigned
4nahB00 25 Apr, 2014 3.40.50.620 Assigned
4nahC00 25 Apr, 2014 3.40.50.620 Assigned
4nahD00 25 Apr, 2014 3.40.50.620 Assigned
4nahE00 25 Apr, 2014 3.40.50.620 Assigned
4nahF00 25 Apr, 2014 3.40.50.620 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase
P63820 COAD_STAAW Staphylococcus aureus subsp. aureus MW2 Phosphopantetheine adenylyltransferase