PDB 4n9e

PDB Information

PDB4N9E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based design of 3-aminopyridine-derived amides as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Dragovich, P.S., Zhao, G., Baumeister, T., Bravo, B., Giannetti, A.M., Ho, Y.C., Hua, R., Li, G., Liang, X., Ma, X., O'Brien, T., Oh, A., Skelton, N.J., Wang, C., Wang, W., Wang, Y., Xiao, Y., Yuen, P.W., Zak, M., Zhao, Q., Zheng, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-10-20
Resolution1.720
CATH Insert Date23 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2014 Chopped
B 24 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4n9eA01 07 Mar, 2014 Holding pen
4n9eA02 07 Mar, 2014 3.20.20.70 Assigned
4n9eB01 07 Mar, 2014 Holding pen
4n9eB02 07 Mar, 2014 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase