PDB Information

PDB4N8E
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV.
Namoto, K., Sirockin, F., Ostermann, N., Gessier, F., Flohr, S., Sedrani, R., Gerhartz, B., Trappe, J., Hassiepen, U., Duttaroy, A., Ferreira, S., Sutton, J.M., Clark, D.E., Fenton, G., Beswick, M., Baeschlin, D.K.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2013-10-17
Resolution2.300
CATH Insert Date16 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Feb, 2014 Chopped
B 17 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4n8eA01 07 Mar, 2014 3.40.50.1820 Assigned
4n8eA02 07 Mar, 2014 2.140.10.30 Assigned
4n8eB01 07 Mar, 2014 3.40.50.1820 Assigned
4n8eB02 07 Mar, 2014 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
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