PDB 4n7e

PDB Information

PDB4N7E
MethodX-RAY DIFFRACTION
Host OrganismHomo Sapiens
Gene SourceHomo sapiens
Primary Citation
The identification of AF38469: An orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin.
Schrder, T.J., Christensen, S., Lindberg, S., Langgard, M., David, L., Maltas, P.J., Eskildsen, J., Jacobsen, J., Tagmose, L., Simonsen, K.B., Biilmann Rnn, L.C., de Jong, I.E., Malik, I.J., Karlsson, J.J., Bundgaard, C., Egebjerg, J., Stavenhagen, J.B., Strandbygard, D., Thirup, S., Andersen, J.L., Uppalanchi, S., Pervaram, S., Kasturi, S.P., Eradi, P., Sakumudi, D.R., Watson, S.P.
Bioorg.Med.Chem.Lett.
HeaderSignaling Protein
Released2013-10-15
Resolution2.700
CATH Insert Date02 Feb, 2014

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4n7eA01 07 Mar, 2014 Holding pen
4n7eA02 07 Mar, 2014 2.10.70.80 Assigned
4n7eA03 07 Mar, 2014 3.30.60.270 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q99523 SORT_HUMAN Homo sapiens Sortilin