PDB 4n3r

PDB Information

PDB4N3R
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors.
Huang, H., Guzman-Perez, A., Acquaviva, L., Berry, V., Bregman, H., Dovey, J., Gunaydin, H., Huang, X., Huang, L., Saffran, D., Serafino, R., Schneider, S., Wilson, C., DiMauro, E.F.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-10-07
Resolution1.900
CATH Insert Date15 Dec, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4n3rA00 20 Dec, 2013 3.90.228.10 Assigned
4n3rB00 20 Dec, 2013 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1