PDB Information

PDB4N07
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold.
Nrholm, A.B., Francotte, P., Olsen, L., Krintel, C., Frydenvang, K., Goffin, E., Challal, S., Danober, L., Botez-Pop, I., Lestage, P., Pirotte, B., Kastrup, J.S.
J.Med.Chem.
HeaderMembrane Protein
Released2013-10-01
Resolution1.870
CATH Insert Date24 Nov, 2013

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 25 Nov, 2013 Chopped
B 25 Nov, 2013 Chopped
C 25 Nov, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4n07A01 27 Nov, 2013 3.40.190.10 Assigned
4n07A02 27 Nov, 2013 3.40.190.10 Assigned
4n07B01 27 Nov, 2013 3.40.190.10 Assigned
4n07B02 27 Nov, 2013 3.40.190.10 Assigned
4n07C01 27 Nov, 2013 3.40.190.10 Assigned
4n07C02 27 Nov, 2013 3.40.190.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
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