PDB Information

PDB4MZO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.
Hilpert, H., Mauser, H., Humm, R., Anselm, L., Kuehne, H., Hartmann, G., Gruener, S., Banner, D.W., Benz, J., Gsell, B., Kuglstatter, A., Stihle, M., Thoma, R., Sanchez, R.A., Iding, H., Wirz, B., Haap, W.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-09-30
Resolution1.470
CATH Insert Date14 Sep, 2014

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Chopped
E 15 Sep, 2014 Chopped
F 15 Sep, 2014 Chopped
G 15 Sep, 2014 Chopped
H 15 Sep, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4mzoA00 16 Sep, 2014 3.90.70.10 Assigned
4mzoB00 16 Sep, 2014 3.90.70.10 Assigned
4mzoC00 16 Sep, 2014 3.90.70.10 Assigned
4mzoD00 16 Sep, 2014 3.90.70.10 Assigned
4mzoE00 16 Sep, 2014 3.90.70.10 Assigned
4mzoF00 16 Sep, 2014 3.90.70.10 Assigned
4mzoG00 16 Sep, 2014 3.90.70.10 Assigned
4mzoH00 16 Sep, 2014 3.90.70.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
O70370 CATS_MOUSE Mus musculus Cathepsin S
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