PDB 4muw

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Overview

PDB Information

PDB	4MUW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, Optimization, and Biological Evaluation of Novel Keto-Benzimidazoles as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). Hu, E., Kunz, R.K., Chen, N., Rumfelt, S., Siegmund, A., Andrews, K., Chmait, S., Zhao, S., Davis, C., Chen, H., Lester-Zeiner, D., Ma, J., Biorn, C., Shi, J., Porter, A., Treanor, J., Allen, J.R. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-23
Resolution	2.640
CATH Insert Date	27 Oct, 2013

PDB Images (5)

Image of CATH 4muw

4muw

PDB 4muw

Image of CATH 4muwA

4muwA

PDB Chain 4muwA

Image of CATH 4muwB

4muwB

PDB Chain 4muwB

Image of CATH 4muwA00

4muwA00

CATH Domain 4muwA00

Image of CATH 4muwB00

4muwB00

CATH Domain 4muwB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Oct, 2013	Chopped
B	28 Oct, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4muwA00	02 Nov, 2013	1.10.1300.10	Assigned
4muwB00	02 Nov, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A