PDB 4mti

PDB Information

PDB4MTI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a]indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells.
Shiokawa, Z., Hashimoto, K., Saito, B., Oguro, Y., Sumi, H., Yabuki, M., Yoshimatsu, M., Kosugi, Y., Debori, Y., Morishita, N., Dougan, D.R., Snell, G.P., Yoshida, S., Ishikawa, T.
Bioorg.Med.Chem.
HeaderApoptosis Inhibitor
Released2013-09-19
Resolution2.150
CATH Insert Date15 Dec, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4mtiA00 20 Dec, 2013 1.10.1170.10 Assigned
4mtiB00 20 Dec, 2013 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13490 BIRC2_HUMAN Homo sapiens Baculoviral IAP repeat-containing protein 2
Q13490 BIRC2_HUMAN Homo sapiens Baculoviral IAP repeat-containing protein 2