PDB 4msh

PDB Links
Overview

PDB Information

PDB	4MSH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. Recht, M.I., Sridhar, V., Badger, J., Bounaud, P.Y., Logan, C., Chie-Leon, B., Nienaber, V., Torres, F.E. J Biomol Screen
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-18
Resolution	2.300
CATH Insert Date	18 May, 2014

PDB Images (5)

Image of CATH 4msh

4msh

PDB 4msh

Image of CATH 4mshA

4mshA

PDB Chain 4mshA

Image of CATH 4mshB

4mshB

PDB Chain 4mshB

Image of CATH 4mshA00

4mshA00

CATH Domain 4mshA00

Image of CATH 4mshB00

4mshB00

CATH Domain 4mshB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 May, 2014	Chopped
B	19 May, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mshA00	21 May, 2014	1.10.1300.10	Assigned
4mshB00	21 May, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A