PDB 4mro

PDB Links
Overview

PDB Information

PDB	4MRO
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles. St Jean, D.J., Ashton, K.S., Bartberger, M.D., Chen, J., Chmait, S., Cupples, R., Galbreath, E., Helmering, J., Hong, F.T., Jordan, S.R., Liu, L., Kunz, R.K., Michelsen, K., Nishimura, N., Pennington, L.D., Poon, S.F., Reid, D., Sivits, G., Stec, M.M., Tadesse, S., Tamayo, N., Van, G., Yang, K.C., Zhang, J., Norman, M.H., Fotsch, C., Lloyd, D.J., Hale, C. J.Med.Chem.
Header	Transferase Inhibitor
Released	2013-09-17
Resolution	2.200
CATH Insert Date	11 May, 2014

PDB Images (9)

Image of CATH 4mro

4mro

PDB 4mro

Image of CATH 4mroA

4mroA

PDB Chain 4mroA

Image of CATH 4mroB

4mroB

PDB Chain 4mroB

Image of CATH 4mroA01

4mroA01

CATH Domain 4mroA01

Image of CATH 4mroA02

4mroA02

CATH Domain 4mroA02

Image of CATH 4mroA03

4mroA03

CATH Domain 4mroA03

Image of CATH 4mroB01

4mroB01

CATH Domain 4mroB01

Image of CATH 4mroB02

4mroB02

CATH Domain 4mroB02

Image of CATH 4mroB03

4mroB03

CATH Domain 4mroB03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	12 May, 2014	Chopped
B	12 May, 2014	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mroA01	17 May, 2014	3.40.50.10490	Assigned
4mroA02	17 May, 2014		Holding pen
4mroA03	17 May, 2014		Holding pen
4mroB01	17 May, 2014	3.40.50.10490	Assigned
4mroB02	17 May, 2014		Holding pen
4mroB03	17 May, 2014		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q14397	GCKR_HUMAN	Homo sapiens	Glucokinase regulatory protein
Q14397	GCKR_HUMAN	Homo sapiens	Glucokinase regulatory protein