PDB 4mne

PDB Information

PDB4MNE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure of the BRAF-MEK Complex Reveals a Kinase Activity Independent Role for BRAF in MAPK Signaling.
Haling, J.R., Sudhamsu, J., Yen, I., Sideris, S., Sandoval, W., Phung, W., Bravo, B.J., Giannetti, A.M., Peck, A., Masselot, A., Morales, T., Smith, D., Brandhuber, B.J., Hymowitz, S.G., Malek, S.
Cancer Cell
HeaderTransferase/Transferase Inhibitor
Released2013-09-10
Resolution2.850
CATH Insert Date29 Jun, 2014

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 30 Jun, 2014 Chopped
B 30 Jun, 2014 Chopped
C 30 Jun, 2014 Chopped
D 30 Jun, 2014 Chopped
E 30 Jun, 2014 Chopped
F 30 Jun, 2014 Chopped
G 30 Jun, 2014 Chopped
H 30 Jun, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4mneA01 03 Jul, 2014 3.30.200.20 Assigned
4mneA02 03 Jul, 2014 1.10.510.10 Assigned
4mneB01 02 Jul, 2014 3.30.200.20 Assigned
4mneB02 02 Jul, 2014 1.10.510.10 Assigned
4mneC01 03 Jul, 2014 3.30.200.20 Assigned
4mneC02 03 Jul, 2014 1.10.510.10 Assigned
4mneD01 03 Jul, 2014 3.30.200.20 Assigned
4mneD02 03 Jul, 2014 1.10.510.10 Assigned
4mneE01 03 Jul, 2014 3.30.200.20 Assigned
4mneE02 03 Jul, 2014 1.10.510.10 Assigned
4mneF01 03 Jul, 2014 3.30.200.20 Assigned
4mneF02 03 Jul, 2014 1.10.510.10 Assigned
4mneG01 03 Jul, 2014 3.30.200.20 Assigned
4mneG02 03 Jul, 2014 1.10.510.10 Assigned
4mneH01 02 Jul, 2014 3.30.200.20 Assigned
4mneH02 02 Jul, 2014 1.10.510.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf