PDB Information

PDB4MBJ
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase.
Newhouse, B.J., Wenglowsky, S., Grina, J., Laird, E.R., Voegtli, W.C., Ren, L., Ahrendt, K., Buckmelter, A., Gloor, S.L., Klopfenstein, N., Rudolph, J., Wen, Z., Li, X., Feng, B.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-08-19
Resolution3.600
CATH Insert Date06 Oct, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
B 07 Oct, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4mbjA01 10 Oct, 2013 3.30.200.20 Assigned
4mbjA02 10 Oct, 2013 1.10.510.10 Assigned
4mbjB01 10 Oct, 2013 3.30.200.20 Assigned
4mbjB02 10 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
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