PDB Information

PDB4MBG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceAspergillus fumigatus
Primary Citation
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
Mabanglo, M.F., Hast, M.A., Lubock, N.B., Hellinga, H.W., Beese, L.S.
Protein Sci.
HeaderTransferase
Released2013-08-19
Resolution1.740
CATH Insert Date05 Jan, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped
B 06 Jan, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4mbgA00 09 Jan, 2014 1.25.40.120 Assigned
4mbgB00 27 Jan, 2014 1.50.10.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q4WP27 Q4WP27_ASPFU Aspergillus fumigatus Af293 CaaX farnesyltransferase alpha subunit Ram2
Q4WPS9 Q4WPS9_ASPFU Aspergillus fumigatus Af293 Protein farnesyltransferase subunit beta