PDB Information

PDB4M8X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
GS-8374, a prototype phosphonate-containing inhibitor of HIV-1 protease, effectively inhibits protease mutants with amino acid insertions.
Grantz Saskova, K., Kozisek, M., Stray, K., de Jong, D., Rezaova, P., Brynda, J., van Maarseveen, N.M., Nijhuis, M., Cihlar, T., Konvalinka, J.
J.Virol.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-08-14
Resolution2.050
CATH Insert Date11 May, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 May, 2014 Chopped
B 12 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4m8xA00 17 May, 2014 2.40.70.10 Assigned
4m8xB00 17 May, 2014 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q90JJ9 Q90JJ9_9HIV1 Human immunodeficiency virus 1 Pol polyprotein
Q90JJ9 Q90JJ9_9HIV1 Human immunodeficiency virus 1 Pol polyprotein