PDB 4m7i

PDB Information

PDB4M7I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 5-{4-fluoro-1-[(6-methyl-2-pyridinyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2656157), a Potent and Selective PERK Inhibitor Selected for Preclinical Development
Axten, J.M., Romeril, S.P., Shu, A., Ralph, J., Medina, J.R., Feng, Y., Li, W.H.H., Grant, S.W., Heerding, D.A., Minthorn, E., Mencken, T., Gaul, N., Goetz, A., Stanley, T., Hassell, A.M., Gampe, R.T., Atkins, C., Kumar, R.
To be Published
HeaderTransferase/Transferase Inhibitor
Released2013-08-12
Resolution2.340
CATH Insert Date14 Sep, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4m7iA01 16 Sep, 2014 3.30.200.20 Assigned
4m7iA02 16 Sep, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NZJ5 E2AK3_HUMAN Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 3