PDB Information

PDB4M7B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, Synthesis, Crystallographic Studies, and Preliminary Biological Appraisal of New Substituted Triazolo[4,3-b]pyridazin-8-amine Derivatives as Tankyrase Inhibitors.
Liscio, P., Carotti, A., Asciutti, S., Karlberg, T., Bellocchi, D., Llacuna, L., Macchiarulo, A., Aaronson, S.A., Schuler, H., Pellicciari, R., Camaioni, E.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-08-12
Resolution1.950
CATH Insert Date16 Mar, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2014 Chopped
C 17 Mar, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4m7bA00 25 Apr, 2014 3.90.228.10 Assigned
4m7bC00 17 Apr, 2014 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
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