PDB Information

PDB4M3Q
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors.
Zhang, W., Zhang, D., Stashko, M.A., Deryckere, D., Hunter, D., Kireev, D., Miley, M.J., Cummings, C., Lee, M., Norris-Drouin, J., Stewart, W.M., Sather, S., Zhou, Y., Kirkpatrick, G., Machius, M., Janzen, W.P., Earp, H.S., Graham, D.K., Frye, S.V., Wang, X.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-08-06
Resolution2.720
CATH Insert Date01 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped
B 02 Dec, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4m3qA01 04 Dec, 2013 3.30.200.20 Assigned
4m3qA02 04 Dec, 2013 1.10.510.10 Assigned
4m3qB01 04 Dec, 2013 3.30.200.20 Assigned
4m3qB02 04 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer
Q12866 MERTK_HUMAN Homo sapiens Tyrosine-protein kinase Mer