PDB Information

PDB4M21
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.
Nature
HeaderSignaling Protein/Inhibitor
Released2013-08-05
Resolution1.940
CATH Insert Date01 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped
B 02 Dec, 2013 Chopped
C 02 Dec, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4m21A00 04 Dec, 2013 3.40.50.300 Assigned
4m21B00 04 Dec, 2013 3.40.50.300 Assigned
4m21C00 04 Dec, 2013 3.40.50.300 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas