PDB 4ltc

PDB Links
Overview

PDB Information

PDB	4LTC
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Trivella, D.B., Pereira, A.R., Stein, M.L., Kasai, Y., Byrum, T., Valeriote, F.A., Tantillo, D.J., Groll, M., Gerwick, W.H., Moore, B.S. Chem.Biol.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-07-23
Resolution	2.500
CATH Insert Date	20 Jul, 2014

PDB Images (57)

4ltc

PDB 4ltc

4ltca

PDB Chain 4ltca

4ltcA

PDB Chain 4ltcA

4ltcb

PDB Chain 4ltcb

4ltcB

PDB Chain 4ltcB

4ltcC

PDB Chain 4ltcC

4ltcD

PDB Chain 4ltcD

4ltcE

PDB Chain 4ltcE

4ltcF

PDB Chain 4ltcF

4ltcG

PDB Chain 4ltcG

4ltcH

PDB Chain 4ltcH

4ltcI

PDB Chain 4ltcI

4ltcJ

PDB Chain 4ltcJ

4ltcK

PDB Chain 4ltcK

4ltcL

PDB Chain 4ltcL

4ltcM

PDB Chain 4ltcM

4ltcN

PDB Chain 4ltcN

4ltcO

PDB Chain 4ltcO

4ltcP

PDB Chain 4ltcP

4ltcQ

PDB Chain 4ltcQ

4ltcR

PDB Chain 4ltcR

4ltcS

PDB Chain 4ltcS

4ltcT

PDB Chain 4ltcT

4ltcU

PDB Chain 4ltcU

4ltcV

PDB Chain 4ltcV

4ltcW

PDB Chain 4ltcW

4ltcX

PDB Chain 4ltcX

4ltcY

PDB Chain 4ltcY

4ltcZ

PDB Chain 4ltcZ

4ltca00

CATH Domain 4ltca00

4ltcA00

CATH Domain 4ltcA00

4ltcb00

CATH Domain 4ltcb00

4ltcB00

CATH Domain 4ltcB00

4ltcC00

CATH Domain 4ltcC00

4ltcD00

CATH Domain 4ltcD00

4ltcE00

CATH Domain 4ltcE00

4ltcF00

CATH Domain 4ltcF00

4ltcG00

CATH Domain 4ltcG00

4ltcH00

CATH Domain 4ltcH00

4ltcI00

CATH Domain 4ltcI00

4ltcJ00

CATH Domain 4ltcJ00

4ltcK00

CATH Domain 4ltcK00

4ltcL00

CATH Domain 4ltcL00

4ltcM00

CATH Domain 4ltcM00

4ltcN00

CATH Domain 4ltcN00

4ltcO00

CATH Domain 4ltcO00

4ltcP00

CATH Domain 4ltcP00

4ltcQ00

CATH Domain 4ltcQ00

4ltcR00

CATH Domain 4ltcR00

4ltcS00

CATH Domain 4ltcS00

4ltcT00

CATH Domain 4ltcT00

4ltcU00

CATH Domain 4ltcU00

4ltcV00

CATH Domain 4ltcV00

4ltcW00

CATH Domain 4ltcW00

4ltcX00

CATH Domain 4ltcX00

4ltcY00

CATH Domain 4ltcY00

4ltcZ00

CATH Domain 4ltcZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	21 Jul, 2014	Chopped
A	21 Jul, 2014	Chopped
b	21 Jul, 2014	Chopped
B	21 Jul, 2014	Chopped
C	21 Jul, 2014	Chopped
D	21 Jul, 2014	Chopped
E	21 Jul, 2014	Chopped
F	21 Jul, 2014	Chopped
G	21 Jul, 2014	Chopped
H	21 Jul, 2014	Chopped
I	21 Jul, 2014	Chopped
J	21 Jul, 2014	Chopped
K	21 Jul, 2014	Chopped
L	21 Jul, 2014	Chopped
M	21 Jul, 2014	Chopped
N	21 Jul, 2014	Chopped
O	21 Jul, 2014	Chopped
P	21 Jul, 2014	Chopped
Q	21 Jul, 2014	Chopped
R	21 Jul, 2014	Chopped
S	21 Jul, 2014	Chopped
T	21 Jul, 2014	Chopped
U	21 Jul, 2014	Chopped
V	21 Jul, 2014	Chopped
W	21 Jul, 2014	Chopped
X	21 Jul, 2014	Chopped
Y	21 Jul, 2014	Chopped
Z	21 Jul, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ltca00	03 Aug, 2014	3.60.20.10	Assigned
4ltcA00	03 Aug, 2014	3.60.20.10	Assigned
4ltcb00	03 Aug, 2014	3.60.20.10	Assigned
4ltcB00	03 Aug, 2014	3.60.20.10	Assigned
4ltcC00	03 Aug, 2014	3.60.20.10	Assigned
4ltcD00	03 Aug, 2014	3.60.20.10	Assigned
4ltcE00	27 Jul, 2014	3.60.20.10	Assigned
4ltcF00	03 Aug, 2014	3.60.20.10	Assigned
4ltcG00	03 Aug, 2014	3.60.20.10	Assigned
4ltcH00	27 Jul, 2014	3.60.20.10	Assigned
4ltcI00	27 Jul, 2014	3.60.20.10	Assigned
4ltcJ00	03 Aug, 2014	3.60.20.10	Assigned
4ltcK00	03 Aug, 2014	3.60.20.10	Assigned
4ltcL00	03 Aug, 2014	3.60.20.10	Assigned
4ltcM00	27 Jul, 2014	3.60.20.10	Assigned
4ltcN00	27 Jul, 2014	3.60.20.10	Assigned
4ltcO00	27 Jul, 2014	3.60.20.10	Assigned
4ltcP00	27 Jul, 2014	3.60.20.10	Assigned
4ltcQ00	27 Jul, 2014	3.60.20.10	Assigned
4ltcR00	27 Jul, 2014	3.60.20.10	Assigned
4ltcS00	03 Aug, 2014	3.60.20.10	Assigned
4ltcT00	27 Jul, 2014	3.60.20.10	Assigned
4ltcU00	27 Jul, 2014	3.60.20.10	Assigned
4ltcV00	03 Aug, 2014	3.60.20.10	Assigned
4ltcW00	03 Aug, 2014	3.60.20.10	Assigned
4ltcX00	27 Jul, 2014	3.60.20.10	Assigned
4ltcY00	27 Jul, 2014	3.60.20.10	Assigned
4ltcZ00	27 Jul, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5