PDB 4lmn

PDB Information

PDB4LMN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers.
Hatzivassiliou, G., Haling, J.R., Chen, H., Song, K., Price, S., Heald, R., Hewitt, J.F., Zak, M., Peck, A., Orr, C., Merchant, M., Hoeflich, K.P., Chan, J., Luoh, S.M., Anderson, D.J., Ludlam, M.J., Wiesmann, C., Ultsch, M., Friedman, L.S., Malek, S., Belvin, M.
Nature
HeaderTransferase/Transferase Inhibitor
Released2013-07-10
Resolution2.800
CATH Insert Date01 Sep, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4lmnA01 03 Sep, 2013 3.30.200.20 Assigned
4lmnA02 03 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1
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