PDB 4llx

PDB Links
Overview

PDB Information

PDB	4LLX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography. Recht, M.I., Sridhar, V., Badger, J., Bounaud, P.Y., Logan, C., Chie-Leon, B., Nienaber, V., Torres, F.E. J Biomol Screen
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-07-09
Resolution	1.750
CATH Insert Date	09 Mar, 2014

PDB Images (5)

Image of CATH 4llx

4llx

PDB 4llx

Image of CATH 4llxA

4llxA

PDB Chain 4llxA

Image of CATH 4llxB

4llxB

PDB Chain 4llxB

Image of CATH 4llxA00

4llxA00

CATH Domain 4llxA00

Image of CATH 4llxB00

4llxB00

CATH Domain 4llxB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	10 Mar, 2014	Chopped
B	10 Mar, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4llxA00	25 Apr, 2014	1.10.1300.10	Assigned
4llxB00	25 Apr, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A