PDB Information

PDB4LI5
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR).
Ward, R.A., Anderton, M.J., Ashton, S., Bethel, P.A., Box, M., Butterworth, S., Colclough, N., Chorley, C.G., Chuaqui, C., Cross, D.A., Dakin, L.A., Debreczeni, J.E., Eberlein, C., Finlay, M.R., Hill, G.B., Grist, M., Klinowska, T.C., Lane, C., Martin, S., Orme, J.P., Smith, P., Wang, F., Waring, M.J.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-07-02
Resolution2.640
CATH Insert Date15 Sep, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4li5A01 18 Sep, 2013 3.30.200.20 Assigned
4li5A02 18 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor