PDB Information

PDB4LH7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEnterococcus faecalis
Primary Citation
Identification through structure-based methods of a bacterial NAD(+)-dependent DNA ligase inhibitor that avoids known resistance mutations.
Murphy-Benenato, K., Wang, H., McGuire, H.M., Davis, H.E., Gao, N., Prince, D.B., Jahic, H., Stokes, S.S., Boriack-Sjodin, P.A.
Bioorg.Med.Chem.Lett.
HeaderLigase/Ligase Inhibitor
Released2013-06-30
Resolution1.900
CATH Insert Date05 Jan, 2014

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4lh7A01 09 Jan, 2014 1.10.287.610 Assigned
4lh7A02 09 Jan, 2014 3.30.1490.70 Assigned
4lh7A03 09 Jan, 2014 3.30.470.30 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q837V6 DNLJ_ENTFA Enterococcus faecalis V583 DNA ligase
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