PDB Information

PDB4L7D
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Binding Mode and Structure-Activity Relationships around Direct Inhibitors of the Nrf2-Keap1 Complex.
Jnoff, E., Albrecht, C., Barker, J.J., Barker, O., Beaumont, E., Bromidge, S., Brookfield, F., Brooks, M., Bubert, C., Ceska, T., Corden, V., Dawson, G., Duclos, S., Fryatt, T., Genicot, C., Jigorel, E., Kwong, J., Maghames, R., Mushi, I., Pike, R., Sands, Z.A., Smith, M.A., Stimson, C.C., Courade, J.P.
Chemmedchem
HeaderTranscription/Inhibitor
Released2013-06-13
Resolution2.250
CATH Insert Date23 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2014 Chopped
B 24 Feb, 2014 Chopped
C 24 Feb, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4l7dA00 07 Mar, 2014 2.120.10.80 Assigned
4l7dB00 07 Mar, 2014 2.120.10.80 Assigned
4l7dC00 07 Mar, 2014 2.120.10.80 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q14145 KEAP1_HUMAN Homo sapiens Kelch-like ECH-associated protein 1
Q14145 KEAP1_HUMAN Homo sapiens Kelch-like ECH-associated protein 1
Q14145 KEAP1_HUMAN Homo sapiens Kelch-like ECH-associated protein 1